Dr. Ali Abuhaleima
Dr. Ali Abuhaleima
Biography
Dr. Ali Abuhaliema is an Assistant Professor in the School of Applied Medical Sciences at the German Jordanian University (GJU). He received his doctorate (Dr. rer. nat.) in Pharmaceutical Sciences as a DAAD scholar at Saarland University and the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Germany. His doctoral research identified the first small-molecule inhibitors of the oncogenic RNA-binding protein IGF2BP2/IMP2. He also holds an MSc in Clinical Pharmacy from the University of Jordan, completed with a DAAD scholarship, and a BSc in Pharmacy from Al-Azhar University, Gaza.
Before joining GJU, Dr. Abuhaliema spent four years as Senior Scientist and Project Manager at Axxam GmbH in Konstanz, Germany. There he led preclinical drug discovery projects in oncology and rare diseases, including high-throughput screening campaigns and assay development for international pharmaceutical partners. He then served as Assistant Professor of Clinical Pharmacy and Therapeutics at Al-Ahliyya Amman University, where he supervised six MSc theses.
His research lies at the interface of drug discovery and precision medicine, with a focus on cancer. It covers targeted therapeutics, pharmacogenomics, drug repurposing, and gene- and RNA-based therapies, as well as pharmacoepidemiology and clinical outcomes research.
Educational Background
Ph.D. in Pharmaceutical Sciences (Drug Discovery and Cancer Therapeutics), Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Germany, 2020
M.Sc. in Clinical Pharmacy, University of Jordan, Jordan, 2015
B.Sc. in Pharmacy, Al-Azhar University, Gaza, Palestine, 2011
M.Sc. in Clinical Pharmacy, University of Jordan, Jordan, 2015
B.Sc. in Pharmacy, Al-Azhar University, Gaza, Palestine, 2011
Research Interests
- Drug discovery and assay development for cancer targets
- Precision oncology and targeted therapeutics
- Pharmacogenetics and pharmacogenomics
Selected Publications
| 2026 | Ali Abuhaliema, Al-Motassem Yousef, Nirmeen Elmadany, Nemah Awwad, Mohaned Hammad,"Impact of ABCB1 polymorphisms on response to anthracycline chemotherapy in breast cancer patients",Nature Publishing Group UK,Scientific Reports,2026 |
| 2026 | Ali Abuhaliema, Ali Al-Samydai, Tabarek H. Mahmood, Ruqaya Mohammad Ahmed, Tabarak R. Al-Sammarraie, Ahmed S.A. Ali Agha," Engineering exosome-based gene therapies: Tools, targets, and AI-enabled genomic design", Journal of Applied Biology & Biotechnology,2026 |
| 2026 | Hanen Al-Sadir, Ayat Al-Farhood, Al-Motassem Yousef, Rami Abduljabbar, Shayma Abdullah, Ali Abuhaliema, Violet Kasabri,"Genetic Polymorphisms in SCN1A Gene (rs6432860) and Pharmacoresistance to Antiepileptic Drugs Among Jordanian Patients with Epilepsy",Pharmaceuticals,2026 |
| 2026 | Yousef Ijjeh, Nowar Alsarayreh, Dana Alqudah, Nirmeen Elzogheir, Ali Abuhaliema, Mohammad R Shomali, Alqassem Abuarqoub, Mohammad IA Ahmad, Sharif Abdelghany, Alaaldin M Alkilany, Walhan Alshaer,"Aptamer‐Guided CRISPR Systems Delivery: Precision Targeting Strategies, Translational Barriers, and Therapeutic Potential",Advanced Therapeutics,2026 |
| 2026 | Ali Abuhaliema, Lobna Gharaibeh, Eman Jaradat, Mohaned Hammad, Walhan Alshaer,"Non-coding RNAs in gene therapy: mechanisms, delivery strategies, and clinical translation",Pharmacia,2026 |
| 2025 | Sijood Janabi, Lobna Gharaibeh, Ibrahim Aldeeb, Ali Abuhaliema,"Quality of Life Assessment of Breast Cancer Patients Undergoing Chemotherapy in Jordan: A Cross‐Sectional Study",International Journal of Breast Cancer,2025 |
| 2022 | Bara'ah Khaleel, Al-Motassem Yousef, Mazhar Salim Al-Zoubi, Muhammad Al-Ulemat, Ahmad A Masadeh, Ali Abuhaliema, Khalid M Al-Batayneh, Bahaa Al-Trad,"Impact of genetic polymorphisms at the promoter area of IL-10 gene on tacrolimus level in Jordanian renal transplantation recipients",Journal of Medical Biochemistry,2022 |
| 2022 | Charlotte Dahlem, Ali Abuhaliema, Sonja M Kessler, Tarek Kröhler, Ben GE Zoller, Shilpee Chanda, Yingwen Wu, Simon Both, Fabian Müller, Konstantin Lepikhov, Susanne H Kirsch, Stephan Laggai, Rolf Muller, Martin Empting, Alexandra K Kiemer,"First small-molecule inhibitors targeting the RNA-binding protein IGF2BP2/IMP2 for cancer therapy",ACS chemical biology,2022 |
